I obtained my Ph.D. degree from the State University of New York at Buffalo in the laboratory of Dr. Lynne Maquat. There I investigated the molecular defects underlying common glycolytic enzyme deficiencies, and performed some of the earliest studies on nonsense- mediated mRNA decay. I obtained my postdoctoral training with Dr. George Vande Woude at NCI, investigating signal transduction events and cell cycle control points influenced by oncogene function. My present work focuses on Eph/ephrin system and the signal transduction mechanisms that are used by this pathway to regulate cell-cell adhesion and cell movement during development.