Post date: 3/11/19
Research in the laboratory of Yoh-suke Mukouyama is aimed at understanding the molecular control of branching network formation in organ development, with a particular emphasis on two major networks, the nervous and vascular systems, which share several anatomic characteristics, and are often patterned similarly in peripheral tissues including skin, heart, and gut. We have recently extended our research to unanticipated roles of tissue macrophages and microglia in neuronal and vascular development. Advanced whole-mount imaging techniques and genetic manipulations provide powerful tools to address these four independent but thematically interrelated projects studying fundamental questions of branching morphogenesis and patterning of these networks.
- Neuronal influence on vascular branching patterns
- Vascular influence on neuronal guidance
- Myeloid/Macrophage influence on vascular and neuronal development
We have a weekly one-on-one meeting to discuss recent data and ongoing issues, and outline a roadmap for ongoing projects, and have a weekly lab meeting/journal club to improve scientific communication and presentation skill. To present preliminary data and interact with experts in the NIH community, we have a weekly Center Seminar Series, a monthly trans-NIH Joint Angiogenesis Meeting, and a quarterly trans-NIH Developmental Biology Interest Group Workshop. We encourage fellows to interact with career consultants and advisors including the NIH Office of Intramural Training and Education and the NHLBI Office of Education.
Roles and Responsibilities
This position will offer a unique opportunity to work at the intersection of cardiovascular development, neuronal development, myeloid/macrophage biology and stem cell biology. We aim to have students increase their skill sets at a graduate student level through their research accomplishments, knowledge of a wider variety of biomedical problems and experimental techniques.
About You
We seek a highly motivated candidate who has experience of working with molecular genetic tools, imaging, and cell culture techniques.
Post-baccalaureate candidates must meet the criteria in the Post-baccalaureate Intramural Research Training Award Program.
Application
Please send an e-mail to me (mukoyamay@mail.nih.gov) with a curriculum vitae and cover letter describing your previous research experiences. We can set up a time to meet or SKYPE.
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